Efficacy of oral saline plus health education and autonomic nerve exercise on the treatment of postural orthostatic tachycardia syndrome in children / 中华实用儿科临床杂志

Objective To compare the efficacy of oral rehydration salts(ORS),health education and autonomic nervous activity training with health education and autonomic nervous activity training on children with postural orthostatic tachycardia syndrome (POTS).Methods Fifty-two children with POTS based on head-up test or head-up tilt test were divided into ORS treatment group and conventional treatment group.ORS treatment group included 33 children,and they received ORS and health education and autonomic nervous activity training therapy.Conventional treatment group included 19 children who received health education and autonomic nervous activity training therapy only.Telephone follow-ups were made after the therapy for 1-3 months.The contents of follow-up were the compliance of ORS treatment,the implementation of health education and POTS related symptom frequency.Results 1.The compliance of doctor's advice in ORS treatment group was better than that in the conventional treatment group.2.There was no significant difference in the symptom scores before therapy between ORS treatment group and conventional treatment group [(6 ± 3) scores in ORS treatment group vs (5 ± 3) scores in conventional treatment group,t =0.799,P ＞ 0.05].After 1 to 3 months therapy,the symptom scores were significantly lowered in both groups.The symptom scores in ORS treatment group was lower than those of the conventional treatment group[(2 ± 1) scores in ORS treatment group vs(3 ± 1)scores in conventional treatment,t =-2.189,P ＜ 0.05].3.If the therapy was determined to be effective when the symptom scores decreased by at least 2 scores,the effective rate in ORS treatment group was significantly higher than that of the conventional treatment group(78.8％ in ORS treatment group vs 42.1％ in conventional treatment group,x2 =7.169,P ＜ 0.01).Conclusions The efficacy of ORS,health education and autonomic nervous activity training therapy is better than that of the health education and autonomic nervous activity training therapy only in POTS children.

EFFECTS OF THE BREATHING MODE CHARACTERIZED BY PROLONGED EXPIRATION ON RESPIRATORY AND CARDIOVASCULAR RESPONSES AND AUTONOMIC NERVOUS ACTIVITY DURING THE EXERCISE / 体力科学

<b>PURPOSE</b> : The purpose of this study was to clarify the effects of prolonged expiration (PE) on respiratory and cardiovascular responses and autonomic nervous activity during the exercise.<b>METHODS</b> : Twenty-five healthy men (22±1years) were classified according to the breathing mode during the exercise : 2-second inspiration and 4-second expiration in 1 : 2 group, 3-second inspiration and 3-second expiration in 1 : 1 group and normal breathing in control group. The 6-minute exercise was performed at anaerobic threshold (AT) and 60%AT using a cycle ergometer as an exercise protocol. Respiratory rate (RR) and tidal volume (TV) were measured by the expired gas analysis. The power of low- (LF) and high-frequency components (HF) was analyzed from a Holter electrocardiogram to assess the heart rate variability. <b>RESULTS</b> : RR and LF/HF were significantly lower, TV and HF were significantly higher during the exercise of 60%AT and AT in the 1 : 1 and 1 : 2 groups than in the control group (P<0.05 or P<0.01). The increase of HR was significantly lower and that of HF was significantly higher during the exercise at 60%AT in the 1 : 2 group than in the 1 : 1 group (P<0.05). <b>CONCLUSION</b> : PE activated the parasympathetic nervous activity and consequently restrained an excessive increase of HR during the exercise at 60%AT.

THE CHANGE OF AUTONOMIC NERVOUS ACTIVITY AFTER ISOKINETIC EXERCISE / 体力科学

The purpose of this study was to investigate the fluctuation of the recovery period of autonomic nervous activity (ANA) after isokinetic exercise. Sixteen male subjects participated in this study after they turned in their consent forms.The subjects performed isokinetic knee extension-flexion exercise using BIODEX. We obtained the electro-cardiogram during the entire experiment. We calculated their heart rate (HR) and power spectral of R-R interval (LF is low frequency component, and HF is high frequency component. Both indexes were converted to a logarithm transformation as to lnHF and lnLF.) from pre-exercise period (PRE) and post-exercise period (POST).Some researchers reported that ΔlnHF of POST was lower and ΔLF/HF of POST was higher than those of PRE immediately after aerobic exercise; however, this study's results were in complete contrast.In conclusion, we found that the recovery periods after aerobic and isokinetic exercises of ANA are entirely different.

Temperature Dependent Physiological Changes by Footbath-Changes of EGG and hunger sensation- / 日本温泉気候物理医学会雑誌

Footbath have long been used for primary health care or for nursing, however, few researches have been reported. We intended to make footbath a safe physiotherapy or care technique in the modern medicine by more profound researches on footbath. The effect of footbath on the gastric motility was studied because footbath may promote recovery from post-surgical gastric paresis. The effects of footbath on the gastric motility and subjective hunger sensation were monitored in 14 healthy adult females (32±6 yeas old). They signed informed consents and took footbaths at 38, 40, 42°C and control footbath (by a footbath machine). The experiments started after permission of the Ethical Committee of International Research Center for Traditional Medicine.<br>They took footbath after 10-min rest in a sitting position. Each footbath was 30 min long, followed by 10-min rest. The same subject participated in the studies four times at the same time of the day before taking lunch (10:00-14:00). These experiments were in a random order four days apart each other except menstruation periods. Their blood pressure, ECG R-R variability and electro-gastrogram (EGG) were monitored. The subjective hunger sensation was asked before, during and after footbath. The autonomic nervous balance was estimated from FFT analysis of the R-R variability. LF (0.04-0.15Hz) and HF (0.15-0.40Hz) components of the R-R variability were calculated. EGG was also analysed by means of FFT to calculate amplitude and frequency. The results showed the amplitude and frequency of EGG increased depending on temperature. However, the correlation between HF power of R-R variability and amplitude of EGG showed negative correlation. Regarding hunger sensation, more cases felt hunger in 38, 40°C than in control. At 42°C, the amplitude and frequency were apparently higher than in other temperatures, while the hungry cases were less than in 38 or 40°C. These discrepancies may be caused by the artifact due to sweating on the abdominal EGG leads, considering high b wave of EEG at 42°C.<br>In conclusion, it was indicated that footbath may promote gastric motility and induce hunger sensation at 38-40°C in healthy volunteers.

Changes in Cardiac Autonomic Nervous Activity During Menstrual Cycle of Young Women / 体力科学

The purpose of this study was to evaluate the function of cardiac autonomic nervous activity and post-exercise vagal reaction during the menstrual cycle. The subjects were healthy young women (n=13, age 19.9±0.6 years) with normal menstrual cycles. Power spectral analysis of heart rate variability was used to examine cardiac autonomic nervous activity. In addition, the time con stant of heart rate decline for the first 30 sec (T<SUB>30</SUB>) after exercise was used to examine post-exercise vagal reactivation.<BR>Results show that the cardiac autonomic nervous activity changes during the menstrual cycle. Also, T<SUB>30</SUB> shows significant change during the menstrual cycle, especially T<SUB>30</SUB> retardation in the early luteal phase. These results suggest that an imbalance of estradiol and progesterone hormones may be responsible for these changes in cardiac autonomic nervous activity during the menstrual cycle.

Heart Rate Variability during the Bathing in Still Water and Flowing Water / 日本温泉気候物理医学会雑誌

This study was conducted to assess the effects of bathing in still water and in flowing water on the heart rate variability. Eight healthy young males (age 20 to 28) bathed in still water at temperatures of 34°C, 38°C, and 41°C for 20 minutes each. The other eight healthy young males (age 22 to 28) bathed in flowing water at a temperature of 36°C for 30 minutes. Electrocardiograms were recorded before, during, and after the bathing. Subjects sat still for 20 minutes before bathing, and then bathed in water to the axilla in a sitting position. Subjects breathed freely during the experiment. Heart rate variability was estimated with the power spectral analysis using FFT. The power densities in the high frequency (0.15 to 0.50Hz) and low frequency (0.04 to 0.15Hz) areas as obtained from this frequency analysis (HF and LF) as well as the ratio of LF/HF were calculated, and HF was used as index of cardiac parasympathetic activity, LF as index of sympathetic activity with parasympathetic modulation, and LF/HF as index of sympathetic activity.<br>During bathing in still water at 34°C and 36°C, no significant change from the value before the bathing was found in heart rate, HF, LF, or LF/HF. HF and LF significantly decreased during the bathing in still water at 38°C and 41°C, LF/HF significantly increased during the bathing in still water at 38°C, During the bathing in still water at 41°C, we could not calculate LF/HF for many subjects because HF disappeared. During the bathing in water flowing at a moderate speed (1.0m/sec), LF/HF increased significantly. During the bathing in water flowing at a high speed (2.0m/sec), heart rate and LF/HF increased significantly while LF decreased significantly.<br>These results suggest that parasympathetic nervous activities are suppressed and sympathetic nervous activities are enhanced during bathing in still water at temperatures higher than the neutral temperature (34°C), and sympathetic nervous activity is enhanced during the bathing in flowing water at 36°C, However, the effects of respiration rate and tidal-volume on HF, and the validity of the HR variabilities as an index of autonomic nervous activities should be examined in further detail.